Posted by: graemebird | September 2, 2016

Thorazine: Sympathy For The Doctor

I don’t really know why this is such a famous Rolling Stones song.  To me its one of their least musical numbers.  Perhaps I lack the poets sensibility.

For now I just have to use this as a cheat sheet for when I ring Dad tomorrow.  You see they are almost definitely giving him THORAZINE for his hiccups.  Thorazine is making Dads hiccups worse not better.  Its attacking his heart and his brain as well.

This has been part of the mystery of the situation.  Now I understand how the doctors could have cocked it up so badly.  Until you find out more about the situation it seems as if the doctors must be suffering from demon possession.

What is Thorazine (chlorpromazine)?

Chlorpromazine is not approved for use in psychotic conditions related to dementia. Chlorpromazine may increase the risk of death in older adults with dementia-related conditions.

“To make sure chlorpromazine is safe for you, tell your doctor if you have:

  • bone marrow suppression;
  • a brain tumor;
  • heart disease;
  • liver or kidney disease;”

“What should I avoid while taking Thorazine (chlorpromazine)?

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall….”

High doses or long-term use of chlorpromazine can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include uncontrollable muscle movements of your lips, tongue, eyes, face, arms, or legs. The longer you take chlorpromazine, the more likely you are to develop a serious movement disorder. The risk of this side effect is higher in women and older adults.”

 “What other drugs will affect Thorazine (chlorpromazine)?Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking chlorpromazine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.”

The above relevant to zoppiclone.

Chlorpromazine (CPZ), marketed under the trade names Thorazine and Largactil among others, is an antipsychotic medication.”

“Drugs like chlorpromazine or its related derivatives have been prescribed for chronic hiccups. Some patients also benefit from taking baclofen. All these drugs are to be taken strictly under medical advice and supervision as they have significant side effects when taken for long periods.

The cause of chronic hiccups needs to be meticulously looked for and treated accordingly before taking drugs to suppress them.”

“Chlorpromazine is a very effective antagonist of D2 dopamine receptors and similar receptors, such as D3 and D5. Unlike most other drugs of this genre, it also has a high affinity for D1receptors. Blocking these receptors causes diminished neurotransmitter binding in the forebrain, resulting in many different effects. Dopamine, unable to bind with a receptor, causes a feedback loop that causes dopaminergic neurons to release more dopamine. Therefore, upon first taking the drug, patients will experience an increase in dopaminergic neural activity. Eventually, dopamine production of the neurons will drop substantially and dopamine will be removed from the synaptic cleft. At this point, neural activity decreases greatly; the continual blockade of receptors only compounds this effect.[9]

“Thorazine is an antipsychotic. It may increase the risk of death when used to treat mental problems caused by dementia in elderly patients. Most of the deaths were linked to heart problems or infection.”

 

 

 

More later.

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